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Multivalent interactions facilitate
motor-dependent protein accumulation at growing microtubule plus-ends

Maan et al., Nature Cell Biology, December 2022

Key work on microtubule dynamics that makes use of KymoButler as an analysis tool

Depolarizing NaV and Hyperpolarizing KV Channels Are Co-Trafficked in Sensory Neurons

Higerd-Rusli et al., June, 2022.

Using a custom version of KymoButler, the Waxman laboratory carries out research on neuronal trafficking.

KymoButler, a deep learning software for automated kymograph analysis

Jakobs et al., eLife, August 2019.

Our seminal paper on the analysis of line-like structures in images. The original model was trained on just 100 images and is now used by hundreds of researchers around the world.

Mechanochemical Crosstalk Produces Cell-Intrinsic Patterning ...

Dimitracopoulos et al., Curr Biol, 2020.

Here we built a multimodal mechanochemical model to recapitulate a complex experimental workflow, leading to the discovery of an intimate relationship between biochemical signalling and the mechanics of cell division in cancer

FeII4L4 Tetrahedron Binds to Nonpaired DNA Bases

Zhu et al., JACS, July 2019.

A core hypothesis behind our approach is to think about oligonucleotide therapeutics in terms of thermodynamics. In this paper we designed and characterised oligonucleotides and leveraged this knowledge to build machine learning algorithms.

Spotlight Publications

Nashchekin et al., Science, November 2021.

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

Koppers et al., eLife, November 2019.

Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized ...

Turner-Bridger et al., PNAS, September 2018.

Cortical Cell Stiffness Is Independent of Substrate Mechanics

Rheinlaender et al., Nature Material, 2020

Mitotic Rounding Alters Cell Geometry to Ensure Efficient Bipolar Spindle Formation

Lancaster et al., Dev Cell, April 2013.

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

Cioni et al., Cell, January 2019.


Select publications by our team

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