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Publications
Multivalent interactions facilitate
motor-dependent protein accumulation at growing microtubule plus-ends
Key work on microtubule dynamics that makes use of KymoButler as an analysis tool
Maan et al., Nature Cell Biology, December 2022
Depolarizing NaV and Hyperpolarizing KV Channels Are Co-Trafficked in Sensory Neurons
Using a custom version of KymoButler, the Waxman laboratory carries out research on neuronal trafficking.
Higerd-Rusli et al., June, 2022.
KymoButler, a deep learning software for automated kymograph analysis
Our seminal paper on the analysis of line-like structures in images. The original model was trained on just 100 images and is now used by hundreds of researchers around the world.
Jakobs et al., eLife, August 2019.
Mechanochemical Crosstalk Produces Cell-Intrinsic Patterning ...
Here we built a multimodal mechanochemical model to recapitulate a complex experimental workflow, leading to the discovery of an intimate relationship between biochemical signalling and the mechanics of cell division in cancer
Dimitracopoulos et al., Curr Biol, 2020.
FeII4L4 Tetrahedron Binds to Nonpaired DNA Bases
A core hypothesis behind our approach is to think about oligonucleotide therapeutics in terms of thermodynamics. In this paper we designed and characterised oligonucleotides and leveraged this knowledge to build machine learning algorithms.
Zhu et al., JACS, July 2019.
Spotlight Publications
Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons
Koppers et al., eLife, November 2019.
Single-molecule analysis of endogenous β-actin mRNA trafficking reveals a mechanism for compartmentalized ...
Turner-Bridger et al., PNAS, September 2018.
Cortical Cell Stiffness Is Independent of Substrate Mechanics
Rheinlaender et al., Nature Material, 2020
Mitotic Rounding Alters Cell Geometry to Ensure Efficient Bipolar Spindle Formation
Lancaster et al., Dev Cell, April 2013.
Publications
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